منابع مشابه
Lesion bypass by S. cerevisiae Pol ζ alone.
DNA polymerase zeta (Pol ζ) participates in translesion synthesis (TLS) of DNA adducts that stall replication fork progression. Previous studies have led to the suggestion that the primary role of Pol ζ in TLS is to extend primers created when another DNA polymerase inserts nucleotides opposite lesions. Here we test the non-exclusive possibility that Pol ζ can sometimes perform TLS in the absen...
متن کاملRegulation of the Rev1-pol ζ complex during bypass of a DNA interstrand cross-link.
DNA interstrand cross-links (ICLs) are repaired in S phase by a complex, multistep mechanism involving translesion DNA polymerases. After replication forks collide with an ICL, the leading strand approaches to within one nucleotide of the ICL ("approach"), a nucleotide is inserted across from the unhooked lesion ("insertion"), and the leading strand is extended beyond the lesion ("extension"). ...
متن کاملA NOTE ON ζ ′ ′ ( s ) AND ζ ′ ′ ′ ( s )
There is only one pair of non-real zeros of ζ′′(s), and of ζ′′′(s), in the left half-plane. The Riemann Hypothesis implies that ζ′′(s) and ζ′′′(s) have no zeros in the strip 0 ≤ <s < 1 2 . It was shown by Speiser [3] that the Riemann Hypothesis is equivalent to ζ′(s) having no zeros in 0 < σ < 12 (as usual we write s = σ + it). Levinson and Montgomery [2] gave a different proof; moreover, they ...
متن کاملDNA Polymerase ζ-Dependent Lesion Bypass in Saccharomyces cerevisiae Is Accompanied by Error-Prone Copying of Long Stretches of Adjacent DNA
Translesion synthesis (TLS) helps cells to accomplish chromosomal replication in the presence of unrepaired DNA lesions. In eukaryotes, the bypass of most lesions involves a nucleotide insertion opposite the lesion by either a replicative or a specialized DNA polymerase, followed by extension of the resulting distorted primer terminus by DNA polymerase ζ (Polζ). The subsequent events leading to...
متن کاملRiemann ’ s and ζ ( s )
[This document is http://www.math.umn.edu/ ̃garrett/m/complex/notes 2014-15/09c Riemann and zeta.pdf] 1. Riemann’s explicit formula 2. Analytic continuation and functional equation of ζ(s) 3. Appendix: Perron identity [Riemann 1859] exhibited a precise relationship between primes and zeros of ζ(s). A similar idea applies to any zeta or L-function with analytic continuation, functional equation, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: DNA Repair
سال: 2011
ISSN: 1568-7864
DOI: 10.1016/j.dnarep.2011.04.032